January 30, 2023Congrats to Katie for being awarded a ASBMB 2023 Graduate Student Award for Discover BMB in Seattle in March!
January 30, 2023Excited to share Katie’s paper characterizing metabolic reductases of Clostridioides difficile infection is online at Frontiers in Pharmacology! (https://doi.org/10.3389/fphar.2023.1074619). Thanks to the Abt and Zackular labs for their years of collaboration and congrats to Katie!
October 28, 2022The lab was awarded a Center for Translational Chemical Biology (CTCB) Pilot grant for proposed work studying ADO!
March 4, 2022Excited to share Xie’s paper showing hydrazines can be made to be potent selective glox inhibitors is online at JACS (https://doi.org/10.1021/jacs.1c12748). Congrats Xie!
August 19, 2021Excited to share Tom’s paper showing hydrazines can covalently target multiple classes of enzymes is online at ACS Central Science (10.1021/acscentsci.1c00616). Congrats to the whole lab and thanks to our collaborators!
June 9, 2021Congrats to Nate for passing his candidacy exam and becoming a Ph.D. candidate. Keep up the good work!
April 14, 2021Congrats to Megan who has been elected to the Penn State Graduate School Alumni Society (GSAS) Board of Directors!
September 3, 2020The group welcomes Dr. Kyosuke Shishikura to the lab as a new post-doctoral researcher. Welcome Kyosuke!
July 24, 2020Tom presented his work in a talk titled “Discovery of cofactor-derived covalencies using chemical proteomics” at the virtual UPenn Chemistry-Biology Interface summer retreat! Great job Tom!
July 21, 2020Katie presented some of her progress on the chemoproteomic profiling of cofactor-dependent enzymes in Clostridioides difficile (C. difficile) at a meeting of the UPenn C. difficile community!
June 18, 2020Thrilled to share our first BioRxiv preprint about Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes
June 10, 2020Megan was selected for NIDAs DP1 Avenir Program to study genetic and epigenetic targets in addiction. Congratulations!
July 24, 2019The group was awarded a shared grant for the Penn Molecular Therapeutics Chemical Biology group
