Excited to share Katie’s paper characterizing metabolic reductases of Clostridioides difficile infection is online at Frontiers in Pharmacology! (https://doi.org/10.3389/fphar.2023.1074619). Thanks to the Abt and Zackular labs for their years of collaboration and congrats to Katie!

https://doi.org/10.3389/fphar.2023.1074619

Excited to share Xie’s paper showing hydrazines can be made to be potent selective glox inhibitors is online at JACS (https://doi.org/10.1021/jacs.1c12748). Congrats Xie!

https://doi.org/10.1021/jacs.1c12748

 

Excited to share Tom’s paper showing hydrazines can covalently target multiple classes of enzymes is online at ACS Central Science (10.1021/acscentsci.1c00616). Congrats to the whole lab and thanks to our collaborators!

https://pubs.acs.org/doi/10.1021/acscentsci.1c00616

Tom presented his work in a talk titled “Discovery of cofactor-derived covalencies using chemical proteomics” at the virtual UPenn Chemistry-Biology Interface summer retreat! Great job Tom!

Tom CBI

Tom gives talk at the virtual UPenn Chemistry-Biology Interface summer retreat!